It was Aristotle who said, 'There was never a genius without a tincture of madness.' Now, there's even scientific proof. According to a study by the Daily Telegraph out of the UK, people with the gene neuregulin 1 were more likely to score higher on creativity assessments and to have greater creative lifetime achievements than those without it. This gene is associated with psychosis and depression. The trick is to have enough of the gene to be creative but not too much to where you're absolutely bonkers.
This made me think of the movie One Flew Over The Cuckoo's Nest (sorry about the old movie references). The last movie I saw at the box office was Slapshot. This movie had Jack Nicholson, Danny Devito, Christopher Lloyd, and Mr Vargus from Fast Times At Ridgemont High. In this scene, Nicholson helps all of his mentally ill cohorts escape the psyche ward to go on a fishing trip (on someone else's boat). Watch the look on group outcast Harding's face at 0:44 as Nicholson introduces all of them as doctors, except him. I got a feeling there was lots of neuregulin 1 on this boat. "The famous Dr. Scanlon".